MI-192
货号：
18288-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 18288-1mg |
| 描述 | MI-192 is an inhibitor of histone deacetylases (HDACs) that preferentially inhibits HDAC2 (IC50 = 30 nM) and HDAC3 (IC50 = 16 nM) over HDAC1, 4, 6, 7, and 8 (IC50s = 4.8, 5, >10, 4.1, and >10 μM, respectively).1 At 0.1-0.4 μM, it induces differentiation and promotes apoptosis of acute myeloid leukemic cell lines U937, HL60, and Kasumi-1.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Boissinot, M.,Inman, M.,Hempshall, A., et al. Induction of differentiation and apoptosis in leukaemic cell lines by the novel benzamide family histone deacetylase 2 and 3 inhibitor MI-192. Leukemia Research 36, 1304-1310 (2012).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 383.4 |
| 分子式 | C24H21N3O2 |
| CAS号 | 1415340-63-4 |
| 稳定性 | ≥ 2 years |
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