| 货号 | 18000-5mg |
| 描述 | Felbamate is an antiepileptic drug that is effective against seizures in a variety of animal models.1,2 It has inhibitory effects at NMDA (Item No. 14581) and GABAA receptors and at voltage-gated channels.2,3,4 Adverse effects in humans, as well as drug interactions and significant side effects, has resulted in limited utility.5,6 |
| 别名 | ADD 03055; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Löscher, W. Critical review of current animal models of seizures and epilepsy used in the discovery and development of new antiepileptic drugs. Seizure 20(5), 359-368 (2011). 2.White, H.S. Clinical significance of animal seizure models and mechanism of action studies of potential antiepileptic drugs. Epilepsia 38 Suppl 1, S9-S17 (1997). 3.French, J.A., and Gazzola, D.M. New generation antiepileptic drugs: What do they offer in terms of improved tolerability and safety? Ther. Adv. Drug Saf. 2(4), 141-158 (2011). 4.Greenfield, L.J., Jr. Molecular mechanisms of antiseizure drug activity at GABAA receptors. Seizure 22(8), 589-600 (2013). 5.Appleton, R.E. The new antiepileptic drugs. Archives of Disease in Childhood 75(3), 256-262 (1996). 6.Benbadis, S.R., and Tatum, W.O.I. Advances in the treatment of epilepsy. American Family Physician 64(1), 91-98 (2001). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 238.2 |
| 分子式 | C11H14N2O4 |
| CAS号 | 25451-15-4 |
| 稳定性 | ≥ 2 years |
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