Pemirolast (potassium salt)
货号：
17889-5mg 基本售价：
490.0 元 规格：
5 mg
产品信息
概述| 货号 | 17889-5mg |
| 描述 | Pemirolast is a histamine H1 receptor antagonist and a mast cell stabilizer that prevents the release of histamine.1 It also blocks the release of substance P, neurokinin A, and calcitonin gene-related peptide from sensory nerves.2 Pemirolast has been used for the treatment of allergic conjunctivitis.3 |
| 别名 | BMY 26517;TBX; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Yanagihara, Y.,Kasai, H.,Matsui, S., et al. Immunopharmacological studies on TBX, a new antiallergic drug (3). Inhibitory effects on histamine release from lung fragments and bronchoconstriction in guinea pigs. Japanese Journal of Pharmacology 51(1), 83-92 (1989).
2.Tatsushima, Y.,Egashira, N.,Kawashiri, T., et al. Involvement of substance P in peripheral neuropathy induced by paclitaxel but not oxaliplatin. Journal of Pharmacology and Experimental Therapeutics 337(1), 226-235 (2011).
3.Minami, K.,Hossen, M.A., and Kamei, C. Increasing effect by simultaneous use of levocabastine and pemirolast on experimental allergic conjunctivitis in rats. Biological and Pharmaceutical Bullentin 28(3), 473-476 (2005).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 266.3 |
| 分子式 | C10H7N6O • K |
| CAS号 | 100299-08-9 |
| 稳定性 | ≥ 2 years |
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