2-Palmitoyl Glycerol
货号：
17882-5mg 基本售价：
490.0 元 规格：
5 mg
产品信息
概述| 货号 | 17882-5mg |
| 描述 | 2-Arachidonoyl glycerol (2-AG; Item No. 62160) is an endogenous agonist of the CB1 and CB2 cannabinoid receptors. 2-Palmitoyl glycerol is a fatty acid ester that does not bind directly to cannabinoid receptors, nor inhibit adenylyl cyclase, but rather potentiates the activity of 2-AG (and other endocannabinoids) to bind to CB1 and CB2 and inhibit adenylyl cyclase.1 This “entourage” effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release.1 2-Palmitoyl glycerol and related endogenous fatty acid derivatives have been shown to interact with endocannabinoids in the modulation of pain sensitivity.2 |
| 别名 | Glycerol-β-palmitate;2-Hexadecanoyl Glycerol;2-Monopalmitin;2-PG; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Ben-Shabat, S.,Fride, E.,Sheskin, T., et al. An entourage effect: Inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity. European Journal of Pharmacology 353, 23-31 (1998).
2.Walker, J.M.,Krey, J.F.,Chu, C.J., et al. Endocannabinoids and related fatty acid derivatives in pain modulation. Chemistry and Physics of Lipids 121, 159-172 (2002).
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| 运输条件 | Dry ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥95% |
| 计算分子量 | 330.5 |
| 分子式 | C19H38O4 |
| CAS号 | 23470-00-0 |
| 稳定性 | ≥ 1 year |
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