Fomepizole
货号：
17851-500mg 基本售价：
490.0 元 规格：
500 mg
产品信息
概述| 货号 | 17851-500mg |
| 描述 | Fomepizole is a competitive inhibitor of alcohol dehydrogenase, the enzyme that catalyzes metabolism of ethylene glycol and methanol to toxic metabolites.1 At 10 µM in monkeys, it can prevent the formation of toxic alcohol metabolites that generate metabolic acidosis.1 This compound is typically used as an antidote for ethylene glycol or methanol poisoning.2 |
| 别名 | 4-Methylpyrazole; |
| 是否危险品 | 是 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Blomstrand, R.,Östling-Wintzell, H.,Löf, A., et al. Pyrazoles as inhibitors of alcohol oxidation and as important tools in alcohol research: An approach to therapy against methanol poisoning. Proceedings of the National Academy of Sciences of the United States of America 76(7), 3499-3503 (1979).
2.Brent, J.,McMartin, K.,Phillips, S., et al. Fomepizole for the treatment of methanol poisoning. New England Journal of Medicine 344, 424-429 (2001).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 82.1 |
| 分子式 | C4H6N2 |
| CAS号 | 7554-65-6 |
| 稳定性 | ≥ 1 year |
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