AC-55541
货号：
17736-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 17736-1mg |
| 描述 | AC-55541 is a proteinase-activated receptor 2 (PAR2) agonist that displays no activity at other PAR subtypes or at over 30 other receptors involved in nociception and inflammation.1 It stimulates cell proliferation, phosphatidylinositol hydrolysis, and calcium mobilization in in vitro functional assays (pEC50s = 6.7, 5.9, and 6.6, respectively).1 Intrapaw administration of 3-10 mg/kg AC-55541 elicited pronociceptive activity in vivo.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Gardell, L.R.,Ma, J.N.,Seitzberg, J.G., et al. Identification and characterization of novel small-molecule protease-activated receptor 2 agonists. Journal of Pharmacology and Experimental Therapeutics 327(3), 799-808 (2008).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 518.4 |
| 分子式 | C25H20BrN5O3 |
| CAS号 | 916170-19-9 |
| 稳定性 | ≥ 2 years |
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