| 货号 | 17423-5mg |
| 描述 | Daidzein (Item No. 10005166) is an isoflavonoid phytoestrogenic compound found in soybeans, pea pods, clover, kudzu, and other legumes. Dihydrodaidzein is an active, estrogenic metabolite of daidzein.1 It has vasodilatory action on rat isolated aortic rings at 1 µg/ml.2 It stimulates the estrogen receptor-dependent growth of breast cancer MCF-7 cells at micromolar concentrations.3 Dihydrodaidzein is produced by the metabolism of daidzein in colonic bacteria and may be further metabolized to various bioactive compounds, including equol (Item No. 13184).4,5 |
| 别名 | (±)-Dihydrodaidzein;4,7-dihydroxy Isoflavanone; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Franke, A.A.,Lai, J.F., and Halm, B.M. Absorption, distribution, metabolism, and excretion of isoflavonoids after soy intake. Archives of Biochemistry and Biophysics 559, 24-28 (2014). 2.Chin-Disting, J.P.F.,Fisher, L.J.,Lewis, T.V., et al. The vascular activity of some isoflavone metabolites: Implications for a cardioprotective role. British Journal of Pharmacology 133(4), 595-605 (2001). 3.Kinjo, J.,Tsuchihashi, R.,Morita, K., et al. Interactions of phytoestrogens with estrogen receptors α and β (III). Estrogenic activities of soy isoflavone aglycones and their metabolites isolated from human urine. Biological and Pharmaceutical Bullentin 27(2), 185-188 (2004). 4.Rafii, F. The role of colonic bacteria in the metabolism of the natural isoflavone daidzin to equol. Metabolites 5(1), 56-73 (2015). 5.Schröder, D.,Matthies, A.,Engst, W., et al. Identification and expression of genes involved in the conversion of daidzein and genistein by the equol-forming bacterium Slackia isoflavoniconvertens. Applied and Environmental Microbiology 79(11), 3494-3502 (2013). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 256.3 |
| 分子式 | C15H12O4 |
| CAS号 | 17238-05-0 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |