Grifolic Acid
货号:
17398-250ug 基本售价:
490.0 元 规格:
250 ug
产品信息
概述货号 | 17398-250ug |
描述 | GPR120 (free fatty acid receptor 4/FFAR4) is a G protein-coupled receptor expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long-chain free fatty acids. It has been linked to the ability of fatty acids to produce anti-inflammatory effects and to acutely potentiate insulin secretion. Grifolic acid is a selective partial agonist of GPR120 that induces ERK activation and intracellular calcium responses in mouse enteroendocrine STC-1 cells that express GPR120 endogenously, but not those expressing GPR40.1 |
性能供应商 | Cayman |
应用文献 |
1.Sun, Q.,Hirasawa, A.,Hara, T., et al. Structure-activity relationships of GPR120 agonists based on a docking simulation. Molecular Pharmaceutics 78, 804-810 (2010).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 372.5 |
分子式 | C23H32O4 |
CAS号 | 80557-12-6 |
稳定性 | ≥ 2 years |
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