LP44 (hydrochloride)
货号:
17287-1mg 基本售价:
490.0 元 规格:
1 mg
产品信息
概述货号 | 17287-1mg |
描述 | LP44 is a full agonist of the serotonin 5-HT7 receptor (Ki = 0.22 nM) that displays 200- and greater than 1,000-fold selectivity over 5-HT1A(Ki = 52.7 nM) and 5-HT2A(Ki = 326 nM) receptors, respectively.1 It can induce relaxation of substance P-induced guinea pig ileum contraction with an EC50 value of 2.56 μM.1 |
性能供应商 | Cayman |
应用文献 |
1.Leopoldo, M.,Berardi, F.,Colabufo, N.A., et al. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents. J.Med.Chem 47, 6616-6624 (2004).
|
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 488.1 |
分子式 | C27H37N3OS • HCl |
CAS号 | 824958-12-5 |
稳定性 | ≥ 2 years |
声明本官网所有报价均为常温或者蓝冰运输价格,如有产品需要干冰运输,需另外加收干冰运输费。 |