Taurolithocholic Acid (sodium salt)
货号：
17275-5mg 基本售价：
490.0 元 规格：
5 mg
产品信息
概述| 货号 | 17275-5mg |
| 描述 | Taurolithocholic acid is a hydrophobic bile acid formed in the liver by conjugation of lithocholate with taurine that is involved in the emulsification of lipids.1 It can induce apoptosis in hepatocytes at 75 µM and has been used to experimentally produce cholestasis in studies of hepatocellular secretion disorders.2,3 |
| 别名 | NSC 681057; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Beuers, U. Effects of bile acids on hepatocellular signaling and secretion. Yale Journal of Biology and Medicine 70(4), 341-346 (1997).
2.Rust, C.,Wild, N.,Bernt, C., et al. Bile acid-induced apoptosis in hepatocytes is caspase-6-dependent. The Journal of Biological Chemisty 284(5), 2908-2916 (2009).
3.Denk, G.U.,Maitz, S.,Wimmer, R., et al. Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver. Hepatology 52(5), 1758-1768 (2010).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 505.7 |
| 分子式 | C26H44NO5S • Na |
| CAS号 | 6042-32-6 |
| 稳定性 | ≥ 2 years |
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