(±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane
货号：
17249-10mg 基本售价：
490.0 元 规格：
10 mg
产品信息
概述| 货号 | 17249-10mg |
| 描述 | (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (BMC) is a cyclohexane with two mercaptoacetamido groups. It is used, both in vitroandin vivo, to promote the correct folding of proteins that require disulfide bonds for functionality.1,2Forin vitro applications, BMC may be used to facilitate protein refolding of solubilized proteins from inclusion bodies.1,2 Reducing agents, like dithiothreitol, may interfere with refolding. BMC may also be added to the growth medium of cells, including yeast cells, to enhance the folding of proteins with disulfide bonds in vivo.2 |
| 别名 | BMC;Vectrase P; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Willis, M.S.,Hogan, J.K.,Prabhakar, P., et al. Investigation of protein refolding using a fractional factorial screen: A study of reagent effects and interactions. Protein Science 14, 1818-1826 (2005).
2.Woycechowsky, K.J.,Wittrup, K.D., and Raines, R.T. A small-molecule catalyst of protein folding in vitro and in vivo. Chemistry & Biology 6(12), 871-879 (1992).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 262.4 |
| 分子式 | C10H18N2O2S2 |
| CAS号 | 257641-01-3 |
| 稳定性 | ≥ 2 years |
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