Guvacoline (hydrobromide)
货号：
17190-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 17190-1mg |
| 描述 | Guvacoline is a natural alkaloid found in areca nuts that is related to the nootropic, arecoline (Item No. 13662). Guvacoline can act as a full agonist of atrial and ileal muscarinic receptors, although at 15-fold reduced potency compared to arecoline.1 The metabolomics and toxicity of this compound have been reported.2,3 |
| 别名 | Norarecoline; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Wolf-Pflugmann, M.,Lambrecht, G.,Wess, J., et al. Synthesis and muscarinic activity of a series of tertiary and quaternary N-substituted guvacine esters structurally related to arecoline and arecaidine propargyl ester. Arzneimittel-Forschung 39, 539-544 (1989).
2.Giri, S.,Idle, J.R.,Chen, C., et al. A metabolomic approach to the metabolism of the areca nut alkaloids arecoline and arecaidine in the mouse. Chemical Research in Toxicology 19(6), 818-827 (2006).
3.Sundqvist, K.,Liu, Y.,Nair, J., et al. Cytotoxic and genotoxic effects of areca nut-related compounds in cultured human buccal epithelial cells. Cancer Research 49(19), 5294-5298 (1989).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 222.1 |
| 分子式 | C7H11NO2 • HBr |
| CAS号 | 17210-51-4 |
| 稳定性 | ≥ 2 years |
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