OF-1
货号:
17124-1mg 基本售价:
490.0 元 规格:
1 mg
产品信息
概述货号 | 17124-1mg |
描述 | OF-1 is a chemical probe for the bromodomains of the Bromodomain and PHD Finger-containing (BRPF) family of proteins. It binds BRPF1B, BRPF2, and BRPF3 with Kd values of 0.1, 0.5, and 2.4 µM, respectively, as determined by isothermal titration calorimetry. OF-1 increases thermal stability of full length BRPF1B at 1 µM, in the cellular thermal shift assay. It also demonstrates accelerated fluorescence recovery after photobleaching (FRAP) at 5 µM in the BRPF2 FRAP assay. OF-1 shows modest general cytotoxicity. See the Structural Genomics Consortium (SGC) website for further information. |
性能供应商 | Cayman |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 440.3 |
分子式 | C17H18BrN3O4S |
CAS号 | 919973-83-4 |
稳定性 | ≥ 2 years |
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