| 货号 | 17097-10mg |
| 描述 | Monobromobimane is a thiol-reactive fluorogenic probe. It is cell-permeable, reacts rapidly at physiological pH with available thiol groups, and generates a stable fluorescent signal.1 Monobromobimane can be used to evaluate or quantify a variety of compounds containing reactive sulfur or thiol groups, including H2S, glutathione, proteins, and nucleotides.2,3,4,5 The absorption and emission maxima for monobromobimane are 398 and 490 nm, respectively.6 |
| 别名 | MBBr;NSC 608544; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Kosower, N.S.,Kosower, E.M.,Newton, G.L., et al. Bimane fluorescent labels: Labeling of normal human red cells under physiological conditions. Proceedings of the National Academy of Sciences of the United States of America 76(7), 3382-3386 (1979). 2.Klingerman, C.M.,Trushin, N.,Prokopczyk, B., et al. H2S concentrations in the arterial blood during H2S administration in relation to its toxicity and effects on breathing. American Journal of Physiology.Regulatory, Integrative and Comparative Physiology 305(6), R630-R638 (2013). 3.Rice, G.C.,Bump, E.A.,Shrieve, D.C., et al. Quantitative analysis of cellular glutathione by flow cytometry utilizing monochlorobimane: Some applications to radiation and drug resistance in vitro and in vivo. Cancer Research 46, 6105-6110 (1986). 4.Chen, Y.T.,Collins, T.R.L.,Guan, A., et al. Probing conformational changes in human DNA topoisomerase IIα by pulsed alkylation mass spectrometry. The Journal of Biological Chemisty 287(30), 25660-25668 (2012). 5.Cosstick, R.,McLaughlin, L.W., and Eckstein, F. Fluorescent labelling of tRNA and oligodeoxynucleotides using T4 RNA ligase. Nucleic Acids Research 12(4), 1791-1810 (2015). 6.Sabnis, R.W. Handbook of biological dyes and stains: Synthesis and industrial applications. (2010). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 271.1 |
| 分子式 | C10H11BrN2O2 |
| CAS号 | 71418-44-5 |
| 稳定性 | ≥ 2 years |
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