OTS964
货号：
17052-500ug 基本售价：
490.0 元 规格：
500 ug
产品信息
概述| 货号 | 17052-500ug |
| 描述 | OTS964 is an inhibitor of lymphokine-activated killer T cell-originated protein kinase (TOPK; IC50 = 28 nM).1 It specifically blocks cytokinesis, leading to apoptosis, in a broad range of cancer cells.1,2 OTS964 induces apoptosis of human lung cancer cells in mouse xenografts.1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Matsuo, Y.,Park, J.H.,Miyamoto, T., et al. TOPK inhibitor induces complete tumor regression in xenograft models of human cancer through inhibition of cytokinesis. Sci. Transl. Med. 6(259), 259ra145 (2014).
2.Ikeda, Y.,Park, J.H.,Miyamoto, T., et al. T-LAK cell-originated protein kinase (TOPK) as a prognostic factor and a potential therapeutic target in ovarian cancer. Clin. Cancer. Res (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 392.5 |
| 分子式 | C23H24N2O2S |
| CAS号 | 1338542-14-5 |
| 稳定性 | ≥ 2 years |
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