Enoxacin
货号：
16956-500mg 基本售价：
490.0 元 规格：
500 mg
产品信息
概述| 货号 | 16956-500mg |
| 描述 | Enoxacin is a fluoroquinolone that prevents bacterial growth by interfering with DNA replication, inhibiting bacterial DNA gyrase (IC50 = 126 µg/ml) and topoisomerase IV (IC50 = 26.5 µg/ml).1 It demonstrates broad-spectrum antibacterial activity against many Gram-positive and Gram-negative bacteria.1 Its ability to bind to TAR RNA-binding protein 2, a microRNA biosynthesis protein, has been used to enhance the production of microRNAs with tumor suppressor functions to generate tumor-specific growth inhibitory effects in cancer models.2 |
| 别名 | NSC 629661; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Takei, M.,Fukuda, H.,Kishii, R., et al. Target preference of 15 quinolones against Staphylococcus aureus, based on antibacterial activities and target inhibition. Antimicrobial Agents and Chemotherapy 45(12), 3544-3547 (2001).
2.Melo, S.,Villanueva, A.,Moutinho, C., et al. Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proceedings of the National Academy of Sciences of the United States of America 108(11), 4394-4399 (2011).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 320.3 |
| 分子式 | C15H17FN4O3 |
| CAS号 | 74011-58-8 |
| 稳定性 | ≥ 2 years |
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