| 货号 | 16492-10mg |
| 描述 | Isoprinosine is a complex of acetaminobenzoic acid, dimethylaminoisopropanol, and inosine in a 3:3:1 ratio. It has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production.1,2,3 Through these effects and others, isoprinosine shows antiviral activity and has applications against subacute sclerosing panencephalitis.3,4 It also restores depressed immune responses in cancer patients after irradiation and reduces the incidence of infection in leukemia patients undergoing chemotherapy.3 |
| 别名 | Inosine pranobex;NP 113;NPT 10381; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Fischbach, M. and Talal, N. Ability of isoprinosine to restore interleukin-2 production and T cell proliferation in autoimmune mice. Clinical and Experimental Immunology 61, 242-247 (1985). 2.Tsang, K.Y.,Fudenberg, H.H.,Galbraith, G.M.P., et al. Partial restoration of impaired interleukin-2 production and tac antigen (putative interleukin-2 receptor) expression in patients with acquired immune deficiency syndrome by isoprinosine treatment in vitro. Journal of Clinical Investigation 75, 1538-1544 (2015). 3.Caspritz, G. and Hadden, J. The immunopharmacology of immunotoxicology, and immunorestoration. Toxicologic Pathology 15(3), 320-332 (1987). 4.Garg, R.K. Subacute sclerosing panencephalitis. Postgrad.Med.J. 78, 63-70 (2015). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 1115.2 |
| 分子式 | C10H12N4O5 • 3C9H9NO3 • 3C5H13NO |
| CAS号 | 36703-88-5 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |