Heat Shock Protein Inhibitor I
货号：
15395-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 15395-1mg |
| 描述 | Heat shock protein (Hsp) inhibitor I is a benzylidene lactam compound that prevents the synthesis of inducible Hsps Hsp105, Hsp72, and Hsp40. At 100 μM, it can inhibit the development of thermotolerance in COLO 320 DM cells.1 Its effects on thermotolerance have been studied in the context of clinical fractionated hyperthermia as a modality of cancer therapy.2 |
| 别名 | Hsp Inhibitor I;KNK 437; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Yokota, S.,Kitahara, M. and Nagata, K. Benzylidene lactam compound, KNK437, a novel inhibitor of acquisition of thermotolerance and heat shock protein induction in human colon carcinoma cells. Cancer Res. 60(11), 2942-2948 (2000).
2.Koishi, M.,Yokota, S.,Mae, T., et al. The effects of KNK437, a novel inhibitor of heat shock protein synthesis, on the acquisition of thermotolerance in a murine transplantable tumor in vivo. Clin. Cancer Res. 7(1), 215-219 (2001).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 245.2 |
| 分子式 | C13H11NO4 |
| CAS号 | 218924-25-5 |
| 稳定性 | ≥ 2 years |
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