MLS-573151
货号：
15269-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 15269-1mg |
| 描述 | The Rho family of GTPases regulates diverse signal transduction pathways. One member, the cell division control protein 42 homolog (Cdc42), is involved in filopodia function, cell polarity, cell cycling, and other processes.1 MLS-573151 is a specific, cell permeable inhibitor of Cdc42 (IC50 = 2 μM).2 It has no effect on other GTPases, including the related Rho family members RhoA, Rac1, and Rac2.2 It acts by blocking the binding of GTP to Cdc42.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Bustelo, X.R.,Sauzeau, V. and Berenjeno, I.M. GTP-binding proteins of the Rho/Rac family: Regulation, effectors and functions in vivo. BioEssays 29(4), 356-370 (2007).
2.Surviladze, Z.,Waller, A.,Wu, Y., et al. Identification of a small GTPase inhibitor using a high-throughput flow cytometry bead-based multiplex assay. Journal of Biomolecular Screening 15(1), 10-20 (2013).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 377.5 |
| 分子式 | C21H19N3O2S |
| CAS号 | 10179-57-4 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
