| 货号 | 14993-10mg |
| 描述 | Suc-AAPF-pNA is a chromogenic substrate that can be cleaved by cathepsin G (Km = 1.7 mM), subtilisins, chymotrypsin (Km = 60 µM), chymase (Km = 4 mM), and cyclophilin, but not neutrophil elastase.1,2,3,4 Release of p-nitroanilide is monitored at 405-410 nm. This substrate can be used for inhibitor screening and kinetic analysis. |
| 别名 | Succinyl-Ala-Ala-Pro-Phe-p-nitroanilide; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Nakajima, K. and Powers, J.C. Mapping the extended substrate binding site of cathepsin G and human leukocyte elastase. The Journal of Biological Chemisty 254(10), 4027-4032 (1979). 2.Ermolieff, J.,Boudier, C.,Laine, A., et al. Heparin protects cathepsin G against inhibition by protein proteinase inhibitors. J.Biol.Chem 269(47), 29502-29508 (1994). 3.Kofron, J.L.,Kuzmic, P.,Kishore, V., et al. Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay. Biochemistry 30(25), 6127-6134 (1991). 4.Nakakubo, H.,Fukuyama, H.,Nakajima, M., et al. Secretory production of recombinant human chymase as an active form in Pichia pastoris. Yeast 16(4), 315-323 (2000). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 624.7 |
| 分子式 | C30H36N6O9 |
| CAS号 | 70967-97-4 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |