Abacavir (sulfate)
货号：
14746-5mg 基本售价：
490.0 元 规格：
5 mg
产品信息
概述| 货号 | 14746-5mg |
| 描述 | Abacavir is an antiviral analog of guanosine, inhibiting the reverse transcriptase of HIV type 1 with an IC50 value of 5.3 μM.1 This blocks retroviral replication, which assists in retroviral therapy.2 Abacavir, commonly used in combination with other antiretroviral compounds, has been associated with a diagnosis of hypersensitivity syndrome.2,3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Choo, H.,Chong, Y. and Chu, C.K. The role of 2,3-unsaturation on the antiviral activity of anti-HIV nucleosides against 3TC-resistant mutant (M184V). Bioorganic & Medicinal Chemistry Letters 13(12), 1993-1996 (2003).
2.Saag, M.S. Initiation of antiretroviral therapy: Implications of recent findings. Top.HIV Med. 12(3), 83-88 (2004).
3.Phillips, E.J. and Mallal, S.A. Pharmacogenetics of drug hypersensitivity. Pharmacogenomics 11(7), 973-987 (2010).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 384.4 |
| 分子式 | C14H18N6O • H2SO4 |
| CAS号 | 216699-07-9 |
| 稳定性 | ≥ 2 years |
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