Gatifloxacin
货号：
14290-1g 基本售价：
490.0 元 规格：
1 g
产品信息
概述| 货号 | 14290-1g |
| 描述 | Gatifloxacin is a fluoroquinolone antibiotic which inhibits bacterial DNA gyrase (IC50 = 0.109 μg/ml) and topoisomerase IV (IC50 = 13.8 μg/ml).1 It is much less effective against HeLa cell topoisomerase II (IC50 = 265 μg/ml).1 Gatifloxin has been used as a broad-spectrum oral antibiotic, but it can produce dysglycemia in older adults.2 It remains useful for resolving bacterial conjunctivitis.3 |
| 别名 | AM1155;BMS 206584-01;PD 135432; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Takei, M.,Fukuda, H.,Yasue, T., et al. Inhibitory activities of gatifloxacin (AM-1155), a newly developed fluoroquinolone, against bacterial and mammalian type II topoisomerases. Antimicrobial Agents and Chemotherapy 42(10), 2678-2681 (1998).
2.Park-Wyllie, L.Y.,Juurlink, D.N.,Kopp, A., et al. Outpatient gatifloxacin therapy and dysglycemia in older adults. New England Journal of Medicine 354(13), 1352-1361 (2006).
3.Cervantes, L.J. and Mah, F.S. Clinical use of gatifloxacin ophthalmic solution for treatment of bacterial conjunctivitis. Clin.Ophthalmol. 5, 495-502 (2011).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 375.4 |
| 分子式 | C19H22FN3O4 |
| CAS号 | 112811-59-3 |
| 稳定性 | ≥ 2 years |
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