Tetrahydromagnolol
货号：
14234-5mg 基本售价：
490.0 元 规格：
5 mg
产品信息
概述| 货号 | 14234-5mg |
| 描述 | Magnolol is a bioactive compound isolated from the bark of M. officinalis that has been used in Asian traditional medicine for the treatment of anxiety, sleep disorders, and allergic diseases. It can activate cannabinoid (CB) receptors, behaving as a partial agonist with selectivity for the peripheral CB2 subtype (EC50 = 3.28 μM; Ki = 1.44 μM).1 Tetrahydromagnolol is a major metabolite of magnolol that is 19-fold more potent than magnolol as a peripheral CB2 receptor agonist (EC50 = 0.17 μM; Ki = 0.42 μM).1 It also behaves as an antagonist at GPR55, a CB-related orphan receptor (KB = 13.3 μM).1 |
| 别名 | Magnolignan; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Rempel, V.,Fuchs, A.,Hinz, S., et al. Magnolia extract, magnolol, and metabolites: Activation of cannabinoid CB2 receptors and blockade of the related GPR55. ACS Med.Chem.Lett. 4, 41-45 (2013).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 270.4 |
| 分子式 | C18H22O2 |
| CAS号 | 20601-85-8 |
| 稳定性 | ≥ 2 years |
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