Acyclovir
货号：
14160-25mg 基本售价：
490.0 元 规格：
25 mg
产品信息
概述| 货号 | 14160-25mg |
| 描述 | Acyclovir is a guanosine analog with antiviral activity in vitro against the herpes simplex viruses, varicella zoster virus, Epstein-Barr virus, cytomegalovirus, and human herpes virus 6 (ID50s = 0.1 - 63.1 μM).1 Acyclovir differs from most nucleoside analogs in that it contains only a partial nucleoside structure with an acyclic side chain. It diffuses freely into cells and is selectively converted into acyclo-guanosine monophosphate by a virus-specific thymidine kinase. During DNA replication, the phosphorylated form of acyclovir is preferentially incorporated into viral DNA, resulting in premature chain termination and inhibition of further activity of DNA polymerase.2 |
| 别名 | ACV;BW 248U;NSC 645011; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Balfour, H.H., Jr. Management of cytomegalovirus disease with antiviral drugs. Rev.Infect.Dis. 12(Suppl. 7), S849-S860 (1990).
2.Bean, B. Antiviral therapy: Current concepts and practices. Clin.Microbiol.Rev. 5(2), 146-182 (1992).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 225.2 |
| 分子式 | C8H11N5O3 |
| CAS号 | 59277-89-3 |
| 稳定性 | ≥ 2 years |
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