Almorexant (hydrochloride)
货号：
13638-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 13638-1mg |
| 描述 | Almorexant is a dual antagonist of the orexin 1 and 2 receptors (Kds = 1.3 and 0.17 nM, respectively).1 In a mouse model of narcolepsy, 100 mg/kg almorexant promoted nonrapid eye movement sleep and exacerbated cataplexy.2 |
| 别名 | ACT 078573; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Malherbe, P.,Borroni, E.,Pinard, E., et al. Biochemical and electrophysiological characterization of almorexant, a dual orexin 1 receptor (OX1)/orexin 2 receptor (OX2) antagonist: Comparison with selective OX1 and OX2 antagonists. Molecular Pharmacology 76(3), 618-631 (2015).
2.Black, S.W.,Morairty, S.R.,Fisher, S.P., et al. Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy. Sleep 36(3), 325-336 (2013).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 549.02 |
| 分子式 | C29H31F3N2O3 • HCl |
| CAS号 | 913358-93-7 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
