Gö 6983
货号：
13311-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 13311-1mg |
| 描述 | Gö 6983 inhibits several isoforms of protein kinase C (PKC; IC50 = 7, 7, 6, 10, 60, and 20,000 nM for PKCα, PKCβ, PKCγ, PKCδ, PKCζ, and PKCμ, respectively).1 It provides cardioprotective effects in myocardial ischemia/reperfusion by attenuating contractile dysfunction.2,3 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Gschwendt, M.,Dieterich, S.,Rennecke, J., et al. Inhibition of protein kinase C μ by various inhibitors. Differentiation from protein kinase c isoenzymes. FEBS Letters 392, 77-80 (1996).
2.Peterman, E.E.,Taormina, P., II,Harvey, M., et al. Gö 6983 exerts cardioprotective effects in myocardial ischemia/reperfusion. Journal of Cardiovascular Pharmacology 43, 645-656 (2004).
3.Young, L.H.,Balin, B.J., and Weis, M.T. Gö 6983: A fast acting protein kinase C inhibitor that attenuates myocardial ischemia/reperfusion injury. Cardiovascular Drug Reviews 23(3), 255-272 (2005).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 442.5 |
| 分子式 | C26H26N4O3 |
| CAS号 | 133053-19-7 |
| 稳定性 | ≥ 2 years |
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