Halopemide
货号：
13205-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 13205-1mg |
| 描述 | Halopemide is a potent inhibitor of phospholipase D (PLD), inhibiting human PLD1 and PLD2in vitro(IC50 = 220 and 310 nM, respectively) and PLD activity in cells.1 Previously, halopemide has been found to inhibit dopamine receptors and was evaluated as a neuroleptic agent.2 |
| 别名 | NSC 354856;R34301; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Scott, S.A.,Selvy, P.E.,Buck, J.R., et al. Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Nature Chemical Biology 5(2), 108-117 (2009).
2.Seeman, P.,Grigoriadis, D.E., and Niznik, H.B. Selectivity of agonists and antagonists at D2 dopamine receptos compared to D1 and S2 receptors. Drug Development Research 9, 63-69 (1986).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 416.9 |
| 分子式 | C21H22ClFN4O2 |
| CAS号 | 59831-65-1 |
| 稳定性 | ≥ 2 years |
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