| 货号 | 11685-1mg |
| 描述 | Bavachin is a flavonoid first isolated from seeds of P. corylifolia. It is a phytoestrogen that activates the estrogen receptors ERα and ERβ (EC50s = 320 and 680 nM, respectively).1,2 Through this action, bavachin stimulates osteoblast proliferation and differentiation and prevents bone loss following ovariectomy in rats.3,4 Bavachin less potently inhibits acyl-coenzyme A:cholesterol acyltransferase (IC50 = 86 µM).5 |
| 别名 | Corylifolin; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Xin, D.,Wang, H.,Yang, J., et al. Phytoestrogens from Psoralea corylifolia reveal estrogen receptor-subtype selectivity. Phytomedicine 17(2), 126-131 (2010). 2.Park, J.,Kim, D.H.,Ahn, H.-N., et al. Activation of estrogen receptor by bavachin from Psoralea corylifolia. Biomol.Ther.(Seoul) 20(2), 183-188 (2012). 3.Li, W.D.,Yan, C.P.,Wu, Y., et al. Osteoblasts proliferation and differentiation stimulating activities of the main components of Fructus Psoraleae corylifoliae. Phytomedicine 21(4), 400-405 (2014). 4.Weng, Z.B.,Gao, Q.Q.,Wang, F., et al. Positive skeletal effect of two ingredients of Psoralea corylifolia L. on estrogen deficiency-induced osteoporosis and the possible mechanisms of action. Mol.Cell.Endocrinol. 417, 103-113 (2015). 5.Choi, J.H.,Rho, M.C.,Lee, S.W., et al. Bavachin and isobavachalcone, acyl-coenzyme A: Cholesterol acyltransferase inhibitors from Psoralea corylifolia. Arch.Pharm.Res. 31(11), 1419-1423 (2008). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 324.4 |
| 分子式 | C20H20O4 |
| CAS号 | 19879-32-4 |
| 稳定性 | ≥ 2 years |
| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |