Tenuazonic Acid (copper salt)
货号：
11443-1mg 基本售价：
490.0 元 规格：
1 mg
产品信息
概述| 货号 | 11443-1mg |
| 描述 | Tenuazonic acid is one of the major Alternaria mycotoxins commonly found as a natural contaminant in food (LD50 = 548 μg/egg in the chicken embryo toxicity assay).1 Tenuazonic acid contamination has been linked to esophageal cancer in human populations at risk of high exposure. Mice fed 100 mg/kg/day tenuazonic acid orally for 10 months developed precancerous lesions on the esophageal mucosa.2 Microscopic analysis of mucosal epithelial cells from these tenuazonic acid-treated animals reveal pyknosis and marked pleomorphisms in the nuclei, chromatin granulation and increased chromatin mass, irregularities in nuclear contours, and vacuolization in nucleoplasms.2 |
| 别名 | AAC-toxin; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Griffin, G.F. and Chu, F.S. Toxicity of the Alternaria metabolites alternariol, alternariol methyl ether, altenuene, and tenuazonic acid in the chicken embryo assay. Applied and Environmental Microbiology 46(6), 1420-1422 (1983).
2.Yekeler, H.,Bitmis, K.,Ozçelik, N., et al. Analysis of toxic effects of Alternaria toxins on esophagus of mice by light and electron microscopy. Toxicologic Pathology 29, 492-497 (2001).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 197.3 |
| 分子式 | C10H15NO3 |
| CAS号 | 610-88-8 |
| 稳定性 | ≥ 2 years |
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