CAY10573
货号：
10008846-500ug 基本售价：
490.0 元 规格：
500 ug
产品信息
概述| 货号 | 10008846-500ug |
| 描述 | The peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors often used as drug targets for the treatment of metabolic disorders. CAY10573 is a PPAR agonist that displays potent binding at PPARα, γ, and δ with IC50 values of 113, 50, and 223 nM, respectively. It potently transactivates PPARα, γ, and δ with EC50 values of 8, 70, and 500 nM, respectively.1 CAY10573 demonstrates stronger binding and functional activity for PPARγ than the antidiabetic compound rosiglitazone (IC50 = 92 nM; EC50 = 220 nM).1 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Mahindroo, N.,Wang, C.C.,Liao, C.C., et al. Indol-1-yl acetic acids as peroxisome proliferator-activated receptor agonists: Design, synthesis, structural biology, and molecular docking studies. Journal of Medicinal Chemistry 49, 1212-1216 (2006).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 521.6 |
| 分子式 | C33H33NO5 |
| CAS号 | 853652-40-1 |
| 稳定性 | ≥ 2 years |
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