| 货号 | 13932-250mg |
| 描述 | Resveratrol-3-O-D-glycoside (piceide) is a stilbene glycoside and a natural precursor to the polyphenol resveratrol (Item Nos. 70675|10004235). It has anti-inflammatory and anti-oxidative properties.1,2,3,4In vitro, it dose-dependently (2.5-20 µg/ml) decreased IL-17 production in activated human peripheral blood mononuclear cells stimulated with anti-CD3/anti-CD28 monoclonal antibodies.1 In a doxorubicin-induced anti-oxidative stress mouse model, it was more effective than resveratrol at increasing total superoxide dismutase, catalase, and glutathione peroxidase activity in plasma.4 It improved learning and memory in a rat model of vascular dementia and showed promising results in cancer cells in vitro.5,6,7 |
| 别名 | trans-Resveratrol-3-O-β-D-Glucopyranoside; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Lanzilli, G.,Cottarelli, A.,Nicotera, G., et al. Anti-inflammatory effect of resveratrol and polydatin by in vitro IL-17 modulation. Inflammation 35(1), 240-248 (2012). 2.Calabriso, N.,Scoditti, E.,Massaro, M., et al. Multiple anti-inflammatory and anti-atherosclerotic properties of red wine polyphenolic extracts: Differential role of hydroxycinnamic acids, flavonols and stilbenes on endothelial inflammatory gene expression. Eur. J. Nutr. 55(2), 477-489 (2016). 3.Ravagnan, G.,De Filippis, B.,Cartenì, M., et al. Polydatin, a natural precursor of resveratrol, induces β-defensin production and reduces inflammatory response. Inflammation 36(1), 26-34 (2013). 4.Wang, H.-L.,Gao, J.-P.,Han, Y.-L., et al. Comparative studies of polydatin and resveratrol on mutual transformation and antioxidative effect in vivo. Phytomedicine 22(5), 553-559 (2015). 5.Li, R.-P.,Wang, Z.-Z.,Sun, M.-X., et al. Polydatin protects learning and memory impairments in a rat model of vascular dementia. Phytomedicine 19(8-9), 677-681 (2012). 6.De Maria, S.,Scognamiglio, I.,Lombardi, A., et al. Polydatin, a natural precursor of resveratrol, induces cell cycle arrest and differentiation of human colorectal Caco-2 cell. J. Transl. Med. 11, 264 (2013). 7.Hogg, S.J.,Chitcholtan, K.,Hassan, W., et al. Resveratrol, acetyl-resveratrol, and polydatin exhibit antigrowth activity against 3D cell aggregates of the SKOV-3 and OVCAR-8 ovarian cancer cell lines. Obstet. Gynecol. Int. 279591 (2015). | |
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 390.4 |
| 分子式 | C20H22O8 |
| CAS号 | 27208-80-6 |
| 稳定性 | ≥ 2 years |
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