Arachidonoyl Serinol
货号：
62170-5mg 基本售价：
462.0 元 规格：
5 mg
产品信息
概述| 货号 | 62170-5mg |
| 描述 | 2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1receptor.1,2 Replacement of the sn-2 oxygen in the glycerol moiety of 2-AG with a nitrogen atom gives arachidonoyl serinol.3 Arachidonoyl serinol is much more stable than 2-AG. However, it is at least a log less potent as a CB1 receptor agonist than 2-AG.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sugiura, T.,Kodaka, T.,Kondo, S., et al. 2-Arachidonoylglycerol, a putative endogenous cannabinoid receptor ligand, induces rapid, transient elevation of intracellular free Ca2+ in neuroblastoma X glioma hybrid NG108-15 cells. Biochemical and Biophysical Research Communications 229, 58-64 (1996).
2.Sugiura, T.,Kodaka, T.,Kondo, S., et al. Is the cannabinoid CB1 receptor a 2-arachidonoylglycerol receptor? Structural requirements for triggering a Ca2+ transient in NG108-15 cells. Journal of Biochemistry 122, 890-895 (1997).
3.Khanolkar, A.D.,Abadji, V.,Lin, S., et al. Head group analogs of arachidonylethanolamide, the endogenous cannabinoid ligand. Journal of Medicinal Chemistry 39, 4515-4519 (1996).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 377.6 |
| 分子式 | C23H39NO3 |
| CAS号 | 183718-70-9 |
| 稳定性 | ≥ 1 year |
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