| 货号 | 18815-10mg |
| 描述 | 1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine.1,2 Urinary levels of MIMA are commonly measured to evaluate histamine secretion, particularly in the context of systemic mastocytosis.3,4,5 |
| 别名 | Methylimidazoleacetic Acid;MIMA;MIAA; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Lindell, S.E. and Schayer, R.W. Metabolism of injected [14C] histamine in the kidney of the dog. Br.J.Pharmacol.Chemother. 13(1), 52-53 (1958). 2.Kerr, J.W. Identification of histamine metabolite 1-methyl, 4-imidazole acetic acid in human urine and its absense in status asthmaticus. British Medical Journal 2(5409), 606-608 (1964). 3.van Doormaal, J.J.,van der Veer, E.,van Voorst Vader, P.C., et al. Tryptase and histamine metabolites as diagnostic indicators of indolent systemic mastocytosis without skin lesions. Allergy 67(5), 683-690 (2012). 4.Vos, B.J.,van der Veer, E.,van Voorst Vader, P.C., et al. Diminished reliability of tryptase as risk indicator of mastocytosis in older overweight subjects. Journal of Allergy and Clinical Immunology 135(3), 792-798 (2015). 5.Tsolakis, A.V.,Grimelius, L.,Granerus, G., et al. Histidine decarboxylase and urinary methylimidazoleacetic acid in gastric neuroendocrine cells and tumours. World Journal of Gastroenterology 21(47), 13240-13249 (2015). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 176.6 |
| 分子式 | C6H8N2O2 • HCl |
| CAS号 | 35454-39-8 |
| 稳定性 | ≥ 2 years |
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