Azathioprine
货号:
13987-500mg 基本售价:
462.0 元 规格:
500 mg
产品信息
概述货号 | 13987-500mg |
描述 | Azathioprine is a purine analog with immunosuppressive effects.1 It serves as a prodrug for 6-mercaptopurine, which alters purine processing and DNA synthesis, interfering with the proliferation of lymphocytes and other myeloid cells.1,2 Its immunomodulating actions are used to benefit inflammatory bowel disease, as well as a wide range of additional diseases with immunological or autoimmunological components, including rheumatoid arthritis and lupus nephritis.1,2,3 |
别名 | Azamune;Azoran;BW 57-322;Imuran;NSC 39084; |
性能供应商 | Cayman |
应用文献 |
1.Nielsen, O.H.,Vainer, B. and Rask-Madsen, J. Review article: The treatment of inflammatory bowel disease with 6-mercaptopurine or azathioprine. Alimentary Pharmacology and Therapeutics 15, 1699-1708 (2001). 2.Clunie, G.P.R. and Lennard, L. Relevance of thiopurine methyltransferase status in rheumatology patients receiving azathioprine. Rheumatology 43(1), 13-18 (2004). 3.Appel, G.B. New and future therapies for lupus nephritis. Cleve. Clin. J. Med. 79(2), 134-140 (2012).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥95% |
计算分子量 | 277.3 |
分子式 | C9H7N7O2S |
CAS号 | 446-86-6 |
稳定性 | ≥ 2 years |
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