S-(5-Adenosyl)-L-methionine chloride (hydrochloride)
货号：
13956-1mg 基本售价：
462.0 元 规格：
1 mg
产品信息
概述| 货号 | 13956-1mg |
| 描述 | S-(5-Adenosyl)-L-methionine chloride (SAM) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases.1,2,3 The transfer of a methyl group from SAM to an acceptor produces S-adenosyl-L-homocysteine (Item No. 13603).2 SAM is also metabolized by SAM decarboxlase to give decarboxylated SAM, which is involved in the polyamine pathway that generates spermine.2 Cayman Chemical’s SAM has been purified to remove all S-adenosylhomocysteine, a known inhibitor of most SAM-dependent methyltransferases which is commonly found in other commercially available SAM. In addition, Cayman’s SAM contains no S-methylthioadenosine, a common impurity which may act as a substrate in some assay formats, resulting in high background. |
| 别名 | AdoMet;SAM; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Chiang, P.K. Biological effects of inhibitors of S-adenosylhomocysteine hydrolase. Pharmacology & Therapeutics 77(2), 115-134 (1998).
2.Loenen, W.A.M. S-Adenosylmethionine: Jack of all trades and master of everything? Biochemical Society Transactions 34(2), 330-333 (2006).
3.Chiang, P.K.,Gordon, R.K.,Tal, J., et al. S-adenosylmethionine and methylation. The FASEB Journal 10, 471-480 (1996).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -80 |
| 纯度 | ≥95% |
| 计算分子量 | 507.8 |
| 分子式 | C15H23ClN6O5S • 2HCl |
| CAS号 | 86867-01-8 |
| 稳定性 | ≥ 1 year |
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