Arachidonoyl-N,N-dimethyl amide
货号：
10007293-5mg 基本售价：
462.0 元 规格：
5 mg
产品信息
概述| 货号 | 10007293-5mg |
| 描述 | Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase. Arachidonoyl-N,N-dimethyl amide is an analog of anandamide that exhibits weak or no binding to the human central cannabinoid (CB1) receptor (Ki >1 µM).1 It inhibits rat glial gap junction cell-cell communication 100% at a concentration of 50 µM.2 |
| 别名 | Arachidonic Acid-N,N-dimethyl amide; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sheskin, T.,Hanus, L.,Slager, J., et al. Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor. Journal of Medicinal Chemistry 40, 659-667 (1997).
2.Boger, D.L.,Sato, H.,Lerner, A.E., et al. Arachidonic acid amide inhibitors of gap junction cell-cell communication. Bioorganic & Medicinal Chemistry Letters 9, 1151-1154 (1999).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 331.5 |
| 分子式 | C22H37NO |
| CAS号 | 45280-17-9 |
| 稳定性 | ≥ 1 year |
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