(S)-CCG-1423
货号：
20107-1mg 基本售价：
448.0 元 规格：
1 mg
产品信息
概述| 货号 | 20107-1mg |
| 描述 | (S)-CCG-1423 is a stereoisomer of CCG-1423 (Item No. 10010350), a Rho inhibitor that blocks signaling through myocardin-related transcription factor A (MRTF-A) and serum response factor (SRF).1,2 The S-isomer of CCG-1423 inhibits MRTF-A-dependent cellular events, including SRF-mediated gene expression and cell migration, more potently than the R-isomer.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Evelyn, C.R.,Wade, S.M.,Wang, Q., et al. CCG-1423: a small-molecule inhibitor of RhoA transcriptional signaling. Molecular Cancer Therapeutics 6(8), 2249-2260 (2007).
2.Watanabe, B.,Minami, S.,Ishida, H., et al. Stereospecific inhibitory effects of CCG-1423 on the cellular events mediated by myocardin-related transcription factor A. PLoS One 10(8), (2015).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 454.8 |
| 分子式 | C18H13ClF6N2O3 |
| 稳定性 | ≥ 2 years |
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