货号 | 82250-10mg |
描述 | SNAP is an S-nitrosothiol which serves as a NO donor and a potent vasodilator. Its stability in solution varies from seconds to hours depending on temperature, buffer composition and metal content.1,2,3,4 At pH 6-8 and 37°C, the half-life of SNAP is approximately six hours in the presence of transition metal ion chelators.5,4 |
别名 | S-Nitroso-N-Acetyl-D,L-Penicillamine; |
供应商 | Cayman |
应用文献 | |
1.Butler, A.R., and Rhodes, P. Chemistry, analysis, and biological roles of S-nitrosothiols. Analytical Biochemistry 249, 1-9 (1997). 2.Gasco, A.,Fruttero, R., and Sorba, G. NO-donors: An emerging class of compounds in medicinal chemistry. Farmaco 51, 617-635 (1996). 3.Cook, J.A.,Kim, S.Y.,Teague, D., et al. Convenient colorimetric and fluorometric assays for S-nitrosothiols. Analytical Biochemistry 238, 150-158 (1996). 4.Roy, B.,dHardemare, A.M., and Fontecave, M. New thionitrites: Synthesis, stability, and nitric oxide generation. The Journal of Organic Chemistry 59, 7019-7026 (1994). 5.Singh, R.J.,Hogg, N.,Joseph, J., et al. Mechanism of nitric oxide release from S-nitrosothiols. The Journal of Biological Chemisty 271, 18596-18603 (1996). | |
运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 220.2 |
分子式 | C7H12N2O4S |
CAS号 | 67776-06-1 |
稳定性 | ≥ 2 years |
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