EUK 124
货号：
12500-5mg 基本售价：
434.0 元 规格：
5 mg
产品信息
概述| 货号 | 12500-5mg |
| 描述 | EUK 8 and EUK 134 (Item No. 10006329) are synthetic catalytic scavengers of reactive oxygen species with superoxide dismutase (SOD) and catalase mimetic activity.1 EUK 124 is a structural analog of EUK 8 and EUK 134 with significantly reduced activity. EUK 124 and EUK 8 inhibit superoxide-mediated reduction of an electron acceptor (i.e., SOD mimetic activity), with IC50 values of 5 µM and 0.7 µM, respectively.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Baker, K.,Marcus, C.B.,Huffman, K., et al. Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: A key role for reactive oxygen species in ischemic brain injury. Journal of Pharmacology and Experimental Therapeutics 284(1), 215-221 (1998).
2.Doctrow, S.R.,Huffman, K.,Marcus, C.B., et al. Salen-manganese complexes as catalytic scavengers of hydrogen peroxide and cytoprotective agents: Structure-activity relationship studies. Journal of Medicinal Chemistry 45, 4549-4558 (2002).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 476.8 |
| 分子式 | C20H22ClMnN2O6 |
| CAS号 | 186299-35-4 |
| 稳定性 | ≥ 2 years |
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