1-Palmitoyl Lysophosphatidic Acid
货号：
10010094-1mg 基本售价：
434.0 元 规格：
1 mg
产品信息
概述| 货号 | 10010094-1mg |
| 描述 | 1-Palmitoyl lysophosphatidic acid (1-Palmitoyl LPA) is a LPA analog containing palmitic acid at the sn-1 position. LPA binds to one of at least five different G protein-coupled receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.1,2 Additionally, 1-palmitoyl LPA enhances the action of β-lactam antibiotics (ampicillin, piperacillin, and ceftazidime) on various strains of P. aeruginosa, a pathogen associated with pulmonary disease and pneumonia, via binding both Ca2+ and Mg2+.3 |
| 别名 | 1-Palmitoyl LPA (free acid); |
性能| 供应商 | Cayman |
| 应用文献 |
1.Noguchi, K.,Ishii, S., and Shimizu, T. Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family. The Journal of Biological Chemisty 278(28), 25600-25606 (2003).
2.Moolenaar, W.H. LPA: A novel lipid mediator with diverse biological actions. Trends in Cell Biology 4, 213-219 (1994).
3.Krogfelt, K.A.,Utley, M.,Krivan, H.C., et al. Specific phospholipids enhance the activity of β-lactam antibiotics against Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy 46(3), 377-384 (2000).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 410.5 |
| 分子式 | C19H39O7P |
| CAS号 | 22002-85-3 |
| 稳定性 | ≥ 2 years |
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