L-Biopterin
货号：
10007662-5mg 基本售价：
434.0 元 规格：
5 mg
产品信息
概述| 货号 | 10007662-5mg |
| 描述 | L-Biopterin is the oxidized form of tetrahydro-L-biopterin (BH4), a nitric oxide synthase (NOS) cofactor. L-Biopterin can be reduced to BH4via thioredoxin reductase followed by dihydropteridine reductase or reduced glutathione. It is extremely toxic to human melanocytes in culture (IC50 = 0.2 µM after 48 hrs).1 L-Biopterin is rarely found under physiological conditions except in the epidermis of patients with the depigmentation disorder Vitiligo.2 |
| 别名 | L-erythro-Biopterin;NSC 339699; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Schallreuter, K.U.,Büttner, G.,Pittelkow, M.R., et al. Cytotoxicity of 6-biopterin to human melanocytes. Biochemical and Biophysical Research Communications 204(1), 43-48 (1994).
2.Moore, J.,Wood, J.M., and Schallreuter, K.U. Evidence for specific complex formation between α-melanocyte stimulating hormone and 6(R)-L-erythro-5,6,7,8-tetrahydrobiopterin using near infared fourier transform raman spectroscopy. Biochemistry 38, 15317-15324 (1999).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | >98% |
| 计算分子量 | 237.2 |
| 分子式 | C9H11N5O3 |
| CAS号 | 22150-76-1 |
| 稳定性 | ≥ 2 years |
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