8-bromo-Cyclic GMP (sodium salt)
货号：
15992-5mg 基本售价：
420.0 元 规格：
5 mg
产品信息
概述| 货号 | 15992-5mg |
| 描述 | 8-bromo-Cyclic GMP (8-bromo-cGMP) is a cell-permeable analog of cGMP that exhibits greater resistance to hydrolysis by phosphodiesterases than its parent compound. It preferentially activates cGMP-dependent protein kinase.1 At 1 µM-0.1 mM, 8-bromo-cGMP can inhibit acetylcholine-induced increases in intracellular calcium concentrations.2 |
| 别名 | 8-bromo-cGMP;8-bromo Guanosine 3’,5’-cyclic monophosphate; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Rashatwar, S.S.,Cornwell, T.L. and Lincoln, T.M. Effects of 8-bromo-cGMP on Ca2+ levels in vascular smooth muscle cells: Possible regulation of Ca2+-ATPase by cGMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America 84(16), 5685-5689 (1987).
2.Choi, J. and Farley, J.M. Effects of 8-bromo-cyclic GMP on membrane potential of single swine tracheal smooth muscle cells. Journal of Pharmacology and Experimental Therapeutics 285(2), 588-594 (1998).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 447.1 |
| 分子式 | C10H11BrN5O7P • Na |
| CAS号 | 51116-01-9 |
| 稳定性 | ≥ 2 years |
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