Oligomycin B
货号：
11343-1mg 基本售价：
420.0 元 规格：
1 mg
产品信息
概述| 货号 | 11343-1mg |
| 描述 | Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin B is a nonselective inhibitor of the mitochondrial F1FO ATP synthase. Oligomycin B (1-10 μM) can reduce the rate of ATP depletion in myocardial ischemia and decrease calcium-induced calcium release oscillation frequency of rat sensory neurons.1,2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Grover, G.J., and Malm, J. Pharmacological profile of the selective mitochondrial F1F0 ATP hydrolase inhibitor BMS-199264 in myocardial ischemia. Cardiovasc.Ther. 26, 287-296 (2008).
2.Jackson, J.G., and Thayer, S.A. Mitochondrial modulation of Ca2+-induced Ca2+-release in rat sensory neurons. Journal of Neurophysiology 96, 1093-1104 (2006).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 805.1 |
| 分子式 | C45H72O12 |
| CAS号 | 11050-94-5 |
| 稳定性 | ≥ 2 years |
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