15(S)-HETrE
货号：
36720-25ug 基本售价：
420.0 元 规格：
25 ug
产品信息
概述| 货号 | 36720-25ug |
| 描述 | 15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of DGLA. It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 µM.1 In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.2 |
性能| 供应商 | Cayman |
| 应用文献 |
1.Petrich, K.,Ludwig, P.,Kühn, H., et al. The suppression of 5-lipoxygenation of arachidonic acid in human polymorphonuclear leukocytes by the 15-lipoxygenase product (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid: Structure-activity relationship and mechanism of action. Biochemistry Journal 314, 911-916 (1996).
2.Haviv, F.,Ratajczyk, J.D.,DeNet, R.W., et al. Structural requirements for the inhibition of 5-lipoxygenase by 15-hydroxyeicosa-5,8,11,13-tetraenoic acid analogues. Journal of Medicinal Chemistry 30, 254-263 (1987).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 322.5 |
| 分子式 | C20H34O3 |
| CAS号 | 92693-02-2 |
| 稳定性 | ≥ 2 years |
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