RBC8
货号:
21281-1mg 基本售价:
420.0 元 规格:
1 mg
产品信息
概述货号 | 21281-1mg |
描述 | RBC8 is a small molecule inhibitor of the Ras-like GTPases RalA and RalB that prevents binding of the GTPase to the Ral-binding protein.1 RBC8 has been shown to prevent Ral-mediated spreading of murine embryonic fibroblasts, block anchorage-independent growth of H2122 and H358 lung cancer cell lines (IC50s = 3.5 and 3.4 µM, respectively), and inhibit the growth of H2122 lung cancer xenografts in mice (50 mg/kg i.p.).1 |
性能供应商 | Cayman |
应用文献 |
1.Yan, C.,Liu, D.,Li, L., et al. Discovery and characterization of small molecules that target the GTPase Ral. Nature (2014).
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运输条件 | Room temperature in continental US; may vary elsewhere |
存放说明 | -20 |
纯度 | ≥98% |
计算分子量 | 424.5 |
分子式 | C25H20N4O3 |
CAS号 | 361185-42-4 |
稳定性 | ≥ 2 years |
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