17α-Estradiol
货号：
20776-50mg 基本售价：
420.0 元 规格：
50 mg
产品信息
概述| 货号 | 20776-50mg |
| 描述 | 17α-Estradiol is the natural optical isomer of 17β-estradiol (Item No. 10006315), the major estrogen secreted by the premenopausal ovary. 17α-Estradiol is a less active isomer than its counterpart, displaying 100-fold lower estrogenic activity relative to 17β-estradiol.1 It can inhibit 5α-reductase, which plays a role in regulating hair growth. 17α -estradiol is reported to activate the MAPK/ERK and PI3K-Akt signaling pathways via activation of the estrogen receptor-X and has been shown to be neuroprotective after an ischemic stroke and oxidative stress and in transgenic mice with Alzheimer’s disease.1,2 |
| 别名 | Alfatradiol;α-Estradiol;17-epi Estradiol;NSC 20293;17α-Oestradiol; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Toran-Allerand, C.D.,Tinnikov, A.A.,Singh, R.J., et al. 17α-estradiol: A brain-active estrogen? Endocrinology 146(9), 3843-3850 (2005).
2.Green, P.S.,Bishop, J. and Simpkins, J.W. 17α-estradiol exerts neuroprotective effects on SK-N-SH cells. Journal of Neuroscience 17(2), 511-515 (1997).
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| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 272.4 |
| 分子式 | C18H24O2 |
| CAS号 | 57-91-0 |
| 稳定性 | ≥ 2 years |
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