| 货号 | 20704-1mg |
| 描述 | FlAsH-EDT2 is a pro-fluorescent, membrane-permeable biarsenical compound that binds covalently to a tetracysteine sequence (CCPGCC), which is engineered into target proteins.1,2 It binds proteins that have the CCPGCC tag almost immediately after translation.2FlAsH-EDT2 is commonly used to study protein trafficking, folding, and interactions in living cells or cell lysates.2,3,4 This green-emitting fluorophore is excited at 508 nm, with emission at 528 nm.4 |
| 别名 | Fluorescein Arsenical Helix Binder;Lumio Green; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Griffin, B.A.,Adams, S.R. and Tsien, R.Y. Specific covalent labeling of recombinant protein molecules inside live cells. Science 287(5374), 269-272 (1998). 2.Rudner, L.,Nydegger, S.,Coren.L.V., et al. Dynamic fluorescent imaging of human immunodeficiency virus type 1 gag in live cells by biarsenical labeling. J.Virol. 79(7), 4055-4065 (2005). 3.Luedtke, N.W.,Dexter, R.J.,Fried, D.B., et al. Surveying polypeptide and protein domain conformation and association with FlAsH and ReAsH. Nat.Chem.Biol. 3(12), 779-784 (2007). 4.Perdios, L.,Bunney.T.D.,Warren, S.C., et al. Time-resolved FRET reports FGFR1 dimerization and formation of a complex with its effector PLCγ1. Adv.Biol.Regul. 60, 6-13 (2016). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 664.5 |
| 分子式 | C24H18As2O5S4 |
| CAS号 | 212118-77-9 |
| 稳定性 | ≥ 2 years |
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