Gallocyanine
货号：
20657-10g 基本售价：
420.0 元 规格：
10 g
产品信息
概述| 货号 | 20657-10g |
| 描述 | Gallocyanine is a small molecule blue dye used to stain nuclei. It is known to inhibit Dickkopf-1 (Dkk1), an antagonist of the Wnt pathway. Gallocyanine can disrupt the interaction of Dkk1 with its receptor LRP5/6 (IC50 = 3 µM), thereby activating Wnt/β-catenin signaling.1 Modulation of the Dkk1-LRP5/6 interaction via gallocyanine has been shown to inhibit prostaglandin J2-induced tau phosphorylation at serine396 in primary cortical neurons in vitro.1 |
| 别名 | IIIC3;Alizarine Navy Blue;Anthracene Blue SWGG;Brilliant Chrome Blue P;C.I. 51030;Fast Violet;Mordant Blue 10; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Mpousis, S.,Thysiadis, S.,Avramidis, N., et al. Synthesis and evaluation of gallocyanine dyes as potential agents for the treatment of Alzheimer’s disease and related neurodegenerative tauopathies. Eur. J. Med. Chem. 108, 28-38 (2016).
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| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥95% |
| 计算分子量 | 336.7 |
| 分子式 | C15H13N2O5 • Cl |
| CAS号 | 1562-85-2 |
| 稳定性 | ≥ 2 years |
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