TBB
货号：
14453-5mg 基本售价：
420.0 元 规格：
5 mg
产品信息
概述| 货号 | 14453-5mg |
| 描述 | TBB is an ATP/GTP-competitive inhibitor of casein kinase 2 (CK2; IC50 = 900 µM for rat liver CK2).1 It less potently inhibits CCK2/cyclin A, GSK3β, and phosphorylase kinase (IC50 = 15.6, 11.2, and 8.7 mM, respectively).1,2 It is much less effective against a range of other kinases.1,3 |
| 别名 | NSC 231634;Tetrabromobenzotriazole; |
性能| 供应商 | Cayman |
| 应用文献 |
1.Sarno, S.,Reddy, H.,Meggio, F., et al. Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 (casein kinase-2). FEBS Letters 496(1), 44-48 (2001).
2.De Moliner, E.,Brown, N.R. and Johnson, L.N. Alternative binding modes of an inhibitor to two different kinases. European Journal of Biochemistry 270(15), 3174-3181 (2003).
3.Pagano, M.A.,Bain, J.,Kazimierczuk, Z., et al. The selectivity of inhibitors of protein kinase CK2: An update. Biochem. J. 415(3), 353-365 (2008).
|
| 运输条件 | Room temperature in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% |
| 计算分子量 | 434.7 |
| 分子式 | C6HBr4N3 |
| CAS号 | 17374-26-4 |
| 稳定性 | ≥ 2 years |
声明| 本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。 |
