| 货号 | 11046-1mg |
| 描述 | 2-NBDG is a fluorescently labeled deoxyglucose analog that is used primarily to directly monitor glucose uptake by living cells and tissues.1,2 It is also used as a topical contrast reagent for the detection of neoplasia.3,4 2-NBDG can be used in real-time confocal, high-resolution, or wide-field fluorescence microscopy as well as in flow cytometry.3,5,6,7 |
| 别名 | NBD-Glucose; |
| 供应商 | Cayman |
| 应用文献 | |
| 1.Yoshioka, K.,Takahashi, H.,Homma, T., et al. A novel fluorescent derivative of glucose applicable to the assessment of glucose uptake activity of Escherichia coli. Biochimica et Biophysica Acta 1289(1), 5-9 (1996). 2.Yamada, K.,Saito, M.,Matsuoka, H., et al. A real-time method of imaging glucose uptake in single, living mammalian cells. Nature Protocols 2(3), 753-763 (2007). 3.Nitin, N.,Carlson, A.L.,Muldoon, T., et al. Molecular imaging of glucose uptake in oral neoplasia following topical application of fluorescently labeled deoxy-glucose. International Journal of Cancer 124(11), 1-20 (2009). 4.Thekkek, N.,Maru, D.M.,Polydorides, A.D., et al. Pre-clinical evaluation of fluorescent deoxyglucose as a topical contrast agent for the detection of Barrett’s-associated neoplasia during confocal imaging. Technol.Cancer Res.Treat. 10(5), 431-441 (2011). 5.Loaiza, A.,Porras, O.H. and Barros, L.F. Glutamate triggers rapid glucose transport stimulation in astrocytes as evidenced by real-time confocal microscopy. Journal of Neuroscience 23(19), 7337-7342 (2003). 6.Langsner, R.J.,Middleton, L.P.,Sun, J., et al. Wide-field imaging of fluorescent deoxy-glucose in ex vivo malignant and normal breast tissue. Biomed.Opt.Express 2(6), 1514-1523 (2011). 7.Berney, M.,Weilenmann, H.U. and Egli, T. Flow-cytometric study of vital cellular functions in Escherichia coli during solar disinfection (SODIS). Microbiology 152, 1719-1729 (2006). | |
| 运输条件 | Wet ice in continental US; may vary elsewhere |
| 存放说明 | -20 |
| 纯度 | ≥98% (mixture of α and β) |
| 计算分子量 | 342.3 |
| 分子式 | C12H14N4O8 |
| CAS号 | 186689-07-6 |
| 稳定性 | ≥ 2 years |
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